The IGF/IGFBP system in CNS malignancy
نویسندگان
چکیده
منابع مشابه
The IGF/IGFBP system in CNS malignancy.
The insulin-like growth factor (IGF) system includes IGF-I and IGF-II, the type I and type II IGF receptors, and specific IGF binding proteins (IGFBP-1 to IGFBP-6). These factors regulate both normal and malignant brain growth. Enhanced expression of IGF-I and IGF-II mRNA transcripts has been demonstrated in gliomas, meniningiomas, and other tumours. Abnormal imprinting of IGF-II occurs in glio...
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ژورنال
عنوان ژورنال: Molecular Pathology
سال: 2001
ISSN: 1366-8714
DOI: 10.1136/mp.54.4.227